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CLINICAL AND HISTOLOGICAL STUDIES OF THE CLASSIFICATION AND THE NATURAL COURSE OF THE STRAWBERRY MARK
Author(s) -
Nakayama Hiroko
Publication year - 1981
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1981.tb02546.x
Subject(s) - lesion , pathological , medicine , pathology , hyaline , telangiectasia
Approximately 1250 cases of strawberry mark were encountered during a 16‐year period. The lesions were classified into three major types, (1) plaque type (d), (2) tumor type (Ds, DS, dS) and (3) subcutaneous type (S). The frequency of each clinical type (d, Ds, DS, dS, S) was studied for 1000 lesions. The plaque type was the first in frequency (57%) and the tumor type was the next (40%). The subcutaneous type was much less frequent (3%). The tendency toward spontaneous regression was studied for 308 lesions in 255 cases, which revealed differences in the natural course among clinical types. Lesions of the plaque and subcutaneous types regress with good end results. Those of the tumor type often regress incompletely. The prognosis of a lesion can be predicted fairly well once its clinical type is known. The clinical features of residual lesions have been briefly described. They are telangiectasia, skin redundancy with wrinkles, and protuberance. Histological investigation of 65 lesions in 62 cases including residual lesions showed hyaline degeneration in capillary walls. The pathological aspects of spontaneous regression have also been discussed.