Premium
CORRELATION BETWEEN COMPLEMENT‐FIXING PEMPHIGOID ANTIBODY TITRES AND DISEASE ACTIVITY
Author(s) -
Kurihara Seiichi,
Nishikawa Takeji,
Sugawara Makoto,
Hatano Hitoshi
Publication year - 1980
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1980.tb01955.x
Subject(s) - bullous pemphigoid , bulla (seal) , antibody , pathogenesis , medicine , immunology , complement (music) , pemphigoid , complement system , immunofluorescence , dermatology , chemistry , biochemistry , lung , complementation , gene , phenotype
A positive correlation between complement‐fixing pemphigoid antibody titre and disease activity was observed in 4 of 8 patients with bullous pemphigoid using complement immunofluorescence. The fact that this correlation cannot always be demonstrated seems to contradict the active role of complement‐fixing pemphigoid antibodies in the pathogenesis of bulla formation. The similarity of bullous pemphigoid and herpes gestationis is discussed.