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A CASE OF LICHEN AMYLOIDOSUS WITH RIEHL'S MELANOSIS‐LIKE LESION ON THE FACE
Author(s) -
Masu ShinIchi,
Sato Akihiko,
Seiji Makoto
Publication year - 1979
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1979.tb01895.x
Subject(s) - melanosis , amyloid (mycology) , protein filament , melanin , intermediate filament , pathology , lesion , ultrastructure , anatomy , chemistry , biology , medicine , melanoma , cytoskeleton , biochemistry , genetics , cell
Ultrastructural studies were carried out on the patient who developed lichen amyloidosus and Riehl's melanosis‐like lesion on the legs and face, respectively. In the skin specimens from the face, there were many masses of aggregations of wavy or net‐like filaments which appeared to correspond to Civatte bodies as recognized under the light microscope at the dermo‐epidermal junction. Sometimes, an other kind of filament mass was present in the papilla. These were aggregations of straight and non‐branching filaments and were very similar to so‐called amyloid masses. These amyloid‐like masses, which seemed to be in a developmental stage, consisted of net‐like filaments as well as straight and non‐branching filaments. Therefore, the net‐like filament masses or Civatte bodies seemed to serve a particular role in the formation of these amyloid‐like filament masses. On the other hand, in the skin specimens from the leg, there were many amyloid masses in the papillae and few Civatte bodies in the dermo‐epidermal junction, but no features suggesting that Civatte bodies may serve a role in the formation of amyloid. From these observations, it may be concluded that Civatte bodies will contribute to the formation of amyloid under certain conditions like Riehl's melanosis; however, it is still uncertain whether Civatte bodies also contribute to the formation of amyloid filaments of lichen amyloidosus.