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COLLOID DEGENERATION OF THE SKIN
Author(s) -
Kawashima Yoshio,
Matsubara Tameaki,
Kinbara Takeshi,
Hirone Takae,
Kitamura Kiyotaka,
Himi Akiko,
Ohkubo Tatsuya
Publication year - 1977
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1977.tb01023.x
Subject(s) - amorphous solid , nodule (geology) , dermis , chin , histopathological examination , colloid , pathology , scalp , degeneration (medical) , anatomy , materials science , medicine , chemistry , biology , crystallography , paleontology
A patient with multiple nodules on the chin and scalp is presented. Histologically, the nodules were composed of amorphous materials which also completely filled up the whole dermis. Histochemical observation indicated that the amorphous material in the nodule was a kind of glycoprotein. Electron microscopic examination revealed that the material consists of short wavy fibrils, 60 to 100 A in diameter, and of a low electron‐dense amorphous substance. Biochemical examination supported the view that the amorphous material is so‐called sialomucoid. The nodules were finally diagnosed as colloid degeneration of the skin (nodular type).