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ERYTHROPOIETIC PROTOPORPHYRIA
Author(s) -
Ozasa Shozaburo,
Yamamoto Shoso,
Maeda Motomichi,
Inada Shuichi,
Yanai Shoko,
Takagaki Kenji
Publication year - 1977
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1977.tb01018.x
Subject(s) - erythropoietic protoporphyria , chemistry , protoporphyrin , biochemistry , porphyrin
Three cases of erythropoietic protoporphyria are reviewed. The three patients constitute members of one family. The protoporphyrin content of the red blood cells was high, but porphyrins and their precursors in the urine and faeces were not excessive. Other normal members of the family did not reveal high protoporphyrin content in the red blood cells. Clinical symptoms were itching, swelling, shallow depressed scars and waxy yellow discoloration on the face and brown pigmentation and thickness on the back of the hands after exposure to the sun. The microscopic findings from skin biopsy specimens of the lesions resembled changes of the lipoid proteinosis.