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From CT Scan to Ceramic Bone Graft
Author(s) -
Darsell Jens,
Bose Susmita,
Hosick Howard L.,
Bandyopadhyay Amit
Publication year - 2003
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/j.1151-2916.2003.tb03427.x
Subject(s) - porosity , materials science , fabrication , biocompatible material , ceramic , biomedical engineering , composite material , computed tomography , tomography , radiology , medicine , alternative medicine , pathology
An indirect fused deposition process was used to fabricate controlled‐porosity alumina bone grafts using a computer‐aided‐design file created from computed tomography (CT) scans of a horse's short pastern bone. Structures with both uniform and gradient porosity were fabricated to show the effectiveness of this process for the fabrication of custom orthopedic implants. Cytotoxicity and cell proliferation studies were conducted with different cell lines to show that these bone grafts are biocompatible. Uniaxial compression tests were also conducted to understand the influence of porosity on the mechanical properties of these structures.