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Effect of Chondroitin Sulfate on the Crystal Growth of Hydroxyapatite
Author(s) -
Rhee SangHoon,
Tanaka Junzo
Publication year - 2000
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/j.1151-2916.2000.tb01522.x
Subject(s) - template , phosphoric acid , chondroitin sulfate , crystal growth , precipitation , crystal (programming language) , steric effects , chemical engineering , materials science , hydroxide , calcium hydroxide , sulfate , suspension (topology) , chemistry , crystallography , nanotechnology , inorganic chemistry , stereochemistry , organic chemistry , biochemistry , engineering , glycosaminoglycan , physics , mathematics , homotopy , meteorology , computer science , pure mathematics , programming language
The effect of chondroitin sulfate (ChS) templates on the crystal growth of hydroxyapatite (HAp) was investigated. HAp particles and 60HAp/40ChS hybrid (in wt%) were synthesized by using a precipitation method with a calcium hydroxide suspension and phosphoric acid solutions without and with ChS, respectively. The sizes of HAp crystals formed without ChS templates were around 75 nm × 10 nm while those with ChS templates were around 12 nm × 6 nm. The inhibitory effect of ChS templates on the crystal growth of HAp is explained in terms of organic matrix regulated HAp formation following steric hindrance by adjacent crystals.