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Hydroxyapatite Coating on a Collagen Membrane by a Biomimetic Method
Author(s) -
Rhee SangHoon,
Tanaka Junzo
Publication year - 1998
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/j.1151-2916.1998.tb02734.x
Subject(s) - citric acid , membrane , chelation , coating , simulated body fluid , chemistry , chemical engineering , biomineralization , carbonate , calcium carbonate , materials science , nuclear chemistry , inorganic chemistry , mineralogy , organic chemistry , biochemistry , apatite , engineering
The coating of a carbonate‐containing hydroxyapatite (HAp) on a nonbioactive collagen membrane via a biomimetic method has been investigated. The collagen membranes were soaked in a simulated body fluid (SBF) solution with and without citric acid, and carbonate‐containing HAp formed only in the SBF solution that contained citric acid. The results were explained in terms of the strong chelation ability of citric acid with the calcium ion. Practical application may involve the inclusion of citric acid in the SBF solution to promote the formation of HAp on previously nonbioactive collagen membranes.