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Growth of a Bonelike Apatite Layer on a Substrate by a Biomimetic Process
Author(s) -
Hata Kotaro,
Kokubo Tadashi,
Nakamura Takashi,
Yamamuro Takao
Publication year - 1995
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/j.1151-2916.1995.tb08435.x
Subject(s) - apatite , simulated body fluid , supersaturation , layer (electronics) , substrate (aquarium) , chemical engineering , materials science , mineralogy , chemistry , composite material , geology , organic chemistry , oceanography , engineering
A dense and uniform bonelike apatite layer was formed on a substrate by the following biomimetic method. The substrate was first placed on granular particles of CaO, SiO 2 ‐based glass soaked in a simulated body fluid (SBF) with ion concentrations nearly equal to those of human blood plasma and then soaked in another fluid highly supersaturated with respect to the apatite. The thickness of the apatite layer increased in proportion to the soaking time in the second solution. The rate of increase in the thickness of the apatite layer increased from 0.5 to 7.0 μm/day with increasing temperature of the second solution from 10° to 60°C, increased from 0.15 to 1.7 μm/day with increasing ion concentrations of the second solution from 0.2 to 1.5 times those of the SBF, and doubled by shaking the second solution. These results indicate that the growth of the apatite layer is controlled by mass transport across the interface between the crystal and the fluid.