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RANDOM AMPLIFIED POLYMORPHIC DNA (RAPD) AND PARSIMONY METHODS
Author(s) -
Backeljau Thierry,
Bruyn Luc,
Wolf Hans,
Jordaens Kurt,
Dongen Stefan,
Verhagen Ron,
Winnepenninckx Birgitta
Publication year - 1995
Publication title -
cladistics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.323
H-Index - 92
eISSN - 1096-0031
pISSN - 0748-3007
DOI - 10.1111/j.1096-0031.1995.tb00083.x
Subject(s) - rapd , biology , inheritance (genetic algorithm) , genetics , dna , transformation (genetics) , evolutionary biology , gene , population , genetic diversity , demography , sociology
— Random amplified polymorphic DNA (RAPD) data possess a number of undesirable features for parsimony analysis. These features include their non‐codominant inheritance, their anonymous nature, their different (a)symmetrical transformation probabilities, and their possible GC priming bias. As a consequence, no single parsimony method seems appropriate for RAPD data. Moreover, the presence/absence coding of RAPDs is equivalent to the invalid independent allele model for allozymes. These issues are discussed and the way in which parsimony analysis of RAPDs can be misleading is illustrated.