Premium
A histological and morphometric study on the tissue and cellular distribution of iron in carp Cyprinus carpio L. during chronic waterborne exposure
Author(s) -
Gregorović G.,
KraljKlobučar N.,
Kopjar N.
Publication year - 2008
Publication title -
journal of fish biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.672
H-Index - 115
eISSN - 1095-8649
pISSN - 0022-1112
DOI - 10.1111/j.1095-8649.2008.01841.x
Subject(s) - cyprinus , biology , carp , cytoplasm , staining , hepatocyte , hemosiderin , dietary iron , microbiology and biotechnology , medicine , biochemistry , iron deficiency , fish <actinopterygii> , fishery , immunology , genetics , anemia , in vitro
The effect of long‐term (77 day) exposure of carp Cyprinus carpio to low concentrations of waterborne iron (1 mg Fe‐dextran l −1 ) on accumulation and cellular distribution of iron in the liver was assessed using Perl’s staining and histological observations and morphometric measurements. Accumulation of iron in the liver occurred after 14 days of exposure, when the majority of the iron was found in the sinusoidal endothelium with lower amounts in the cytoplasm and nuclei of hepatocytes. Upon further treatment the iron was predominantly distributed in the cytoplasm of the hepatocytes either as granules or diffusive iron and in macrophages.