Premium
The effects of chronic developmental hypoxia on swimming performance in zebrafish
Author(s) -
Widmer S.,
Moore F. B.G.,
Bagatto B.
Publication year - 2006
Publication title -
journal of fish biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.672
H-Index - 115
eISSN - 1095-8649
pISSN - 0022-1112
DOI - 10.1111/j.1095-8649.2006.01242.x
Subject(s) - biology , hypoxia (environmental) , zebrafish , danio , medicine , endocrinology , physiology , zoology , oxygen , biochemistry , chemistry , organic chemistry , gene
Relative to normoxia‐reared fish, hypoxia‐reared zebrafish Danio rerio achieved 24·9 and 21·4% slower maximal swim velocities in both normoxic and hypoxic waters, respectively. Hypoxia‐reared fish also produced 26·1 and 63·9% less lactate during resting conditions across both normoxic and hypoxic waters, respectively. During exercise, this trend continued as hypoxia‐reared fish produced 68·2 and 55·1% less lactate across both normoxic and hypoxic waters, respectively. This reduction in performance, rather than representing a purely pathological (maladaptive) response to hypoxia, appears to represent a fundamental shift in the metabolic response to hypoxia.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom