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The effects of chronic developmental hypoxia on swimming performance in zebrafish
Author(s) -
Widmer S.,
Moore F. B.G.,
Bagatto B.
Publication year - 2006
Publication title -
journal of fish biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.672
H-Index - 115
eISSN - 1095-8649
pISSN - 0022-1112
DOI - 10.1111/j.1095-8649.2006.01242.x
Subject(s) - biology , hypoxia (environmental) , zebrafish , danio , medicine , endocrinology , physiology , zoology , oxygen , biochemistry , chemistry , organic chemistry , gene
Relative to normoxia‐reared fish, hypoxia‐reared zebrafish Danio rerio achieved 24·9 and 21·4% slower maximal swim velocities in both normoxic and hypoxic waters, respectively. Hypoxia‐reared fish also produced 26·1 and 63·9% less lactate during resting conditions across both normoxic and hypoxic waters, respectively. During exercise, this trend continued as hypoxia‐reared fish produced 68·2 and 55·1% less lactate across both normoxic and hypoxic waters, respectively. This reduction in performance, rather than representing a purely pathological (maladaptive) response to hypoxia, appears to represent a fundamental shift in the metabolic response to hypoxia.