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The role of the pericardium in cardiac function in the dogfish, Squalus acanthias
Author(s) -
Franklin C. E.,
Davie P. S.
Publication year - 1993
Publication title -
journal of fish biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.672
H-Index - 115
eISSN - 1095-8649
pISSN - 0022-1112
DOI - 10.1111/j.1095-8649.1993.tb00423.x
Subject(s) - squalus acanthias , pericardium , cardiac output , biology , cardiac function curve , cardiac cycle , medicine , suction , anatomy , cardiology , blood pressure , heart failure , endocrinology , mechanical engineering , engineering
Opening the pericardium to the ambient bathing fluid surrounding the in situ perfused dogfish ( Squalus acanthias ) heart caused a precipitous fall in cardiac output. Cardiac output fell by 55% despite the rise of mean input pressure from subambient, to near zero levels. Lower cardiac output caused a fall in mean output pressure but not diastolic pressure as this was set by the experimenters. With the pericardium intact, the heart was filled by suction. With an open pericardium the magnitude of negative input pressures was severely reduced. None the less, far short periods within the cardiac cycle, the heart was still able to generate subambient pressures in the atrium and so draw fluid from the central veins.