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The immune response of carp, Cyprinus carpio L., following injection of antigen‐antibody complexes
Author(s) -
Secombes C. J.,
Resink J. W.
Publication year - 1984
Publication title -
journal of fish biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.672
H-Index - 115
eISSN - 1095-8649
pISSN - 0022-1112
DOI - 10.1111/j.1095-8649.1984.tb04790.x
Subject(s) - cyprinus , antigen , biology , carp , adjuvant , antibody , immune system , antibody response , immunology , common carp , priming (agriculture) , fish <actinopterygii> , fishery , botany , germination
Cyprinus carpio immunized with antigen‐antibody complexes formed at equivalence were found to have both good memory and enhanced serum antibody responses compared with fish primed with antigen alone. Only priming with antigen or complex in adjuvent produced comparable results. Complexes formed in antigen excess gave better precipitation responses during the secondary response than in corresponding control groups injected antigen alone or in adjuvant. The role of antigen‐antibody complexes in the fish immune system and the possibility of using such complexes to vaccinate fish are discussed.