Premium
Optimization of assay conditions for, and the selected tissue distribution of, alanine aminotransferase and aspartate aminotransferase of English sole, Parophrys vetulus Girard
Author(s) -
Casillas E.,
Sundquist J.,
Ames W. E.
Publication year - 1982
Publication title -
journal of fish biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.672
H-Index - 115
eISSN - 1095-8649
pISSN - 0022-1112
DOI - 10.1111/j.1095-8649.1982.tb03999.x
Subject(s) - biology , alanine aminotransferase , enzyme , alanine transaminase , fish <actinopterygii> , alanine , kidney , biochemistry , liver enzyme , endocrinology , fishery , amino acid
Optimization of assay conditions for serum alanine aminotransferase (ALAT, GPT) and aspartate aminotransferase (ASAT, GOT) are described for English sole, Parophrys vetulus . Although most conditions for measurement of these fish enzymes parallel conditions in mammals, the optimal pH is lower for both these enzymes. Liver represents a potentially large source of ASAT activity, potential sources for ALAT activity are liver and kidney. As in mammals, the use of these enzymes as indicators of fish liver and kidney dysfunction may be warranted.