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The effect of clomiphene citrate on ovulation and spawning in indomethacin treated carp, Cyprinus carpio
Author(s) -
Kapur K.,
Toor H. S.
Publication year - 1979
Publication title -
journal of fish biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.672
H-Index - 115
eISSN - 1095-8649
pISSN - 0022-1112
DOI - 10.1111/j.1095-8649.1979.tb03495.x
Subject(s) - cyprinus , ovulation , biology , dose , carp , clomifene , endocrinology , induced ovulation , medicine , fishery , pharmacology , fish <actinopterygii> , ovulation induction , hormone
Studies were conducted on the effect of clomiphene on ovulation and spawning in mature C. carpio pre‐treated with indomethacin. It was demonstrated that indomethacin caused a block to ovulation and spawning at two dose levels (5 and 10 μg −1 g). This blockade could be overcome by two (10 μg −1 g each) successive dosages of clomiphene given 7 and 31 h after the indomethacin treatment. When indomethacin and clomiphene treatments were given concomittantly, the inhibitory effects of indomethacin remained more pronounced.