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Effects of 6‐hydroxydopamine and 5‐hydroxydopamine onlthe teleost melanophores innervation
Author(s) -
Junqueira L.C.U.,
Salles L. M. M.
Publication year - 1978
Publication title -
journal of fish biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.672
H-Index - 115
eISSN - 1095-8649
pISSN - 0022-1112
DOI - 10.1111/j.1095-8649.1978.tb03449.x
Subject(s) - hydroxydopamine , chromatophore , biology , monoaminergic , killifish , dopamine , melanophore , anatomy , medicine , endocrinology , dopaminergic , fish <actinopterygii> , fishery , serotonin , biochemistry , receptor
Intraperitoneal injections of 6‐OH‐dopamine (80 mg kg −l ) promote, in toad fish, killifish, lsummer and winter flounders, a darkening of their colour and loss of capacity to adapt tolthe colour of the background. This condition persisted for three weeks after which thelanimals gradually returned to normal. The study of the skin of 6‐hydroxydopamineltreated killifish showed degenerative lesions in the fine nerves and synapses of its melanophores, 124 h after the administration of the drug. These lesions progressed and 4 days later, lno synaptic structures could be detected in these cells. This condition persisted up to thel20th day. These results suggest that melanophores have a single monoaminergic innervaion.