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Phrenic nerve conduction study in CIDP
Author(s) -
Ciaramitaro P,
Poglio F,
Tavella A,
Rota E,
Prolasso I,
Isoardo G,
Baldi S,
Cocito D
Publication year - 2004
Publication title -
journal of the peripheral nervous system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1
H-Index - 67
eISSN - 1529-8027
pISSN - 1085-9489
DOI - 10.1111/j.1085-9489.2004.009209j.x
Subject(s) - medicine , phrenic nerve , pulmonary function testing , compound muscle action potential , vital capacity , cardiology , nerve conduction , respiratory system , nerve conduction velocity , anesthesia , diaphragmatic breathing , electrophysiology , pathology , lung , lung function , alternative medicine , diffusing capacity
Background: Alterations of the phrenic nerve (FN), as well as of the pulmonary function tests (PFTs), have been described in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Objective: Our study was aimed at assessing the relationship between FN conduction study and respiratory function in 24 CIDP patients without clinical signs of respiratory failure. Material and Methods: Bilateral FN and right median nerve conduction studies were accomplished, along with emogasanalysis (EGA) and PFTs: maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), forced vital capacity (FVC) and partial CO 2 pressure. Results: The amplitude of the compound muscle action potential (CMAP) of the FN was altered in 19 (79%) of our 24 patients, the latency in 22 (92%). Eighteen patients (75%) showed at least one PFT or the pCO 2 abnormal. FN alterations showed a low sensitivity and specificity with respect to PFTs or pCO 2 . Discussion: Our results demonstrated electrophysiological alterations of the FN in a high percentage of CIDP patients. No significant correlation was observed between FN and PFTs alterations.