Premium
042
Comparative Evaluation of Duplex‐Derived Parameters in Patients with Chronic Venous Insufficiency: Correlation with Clinical Manifestation
Author(s) -
Takashi Yamaki,
Motohiro Nozaki,
Osamu Fujiwara
Publication year - 2004
Publication title -
wound repair and regeneration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.847
H-Index - 109
eISSN - 1524-475X
pISSN - 1067-1927
DOI - 10.1111/j.1067-1927.2004.abstractbe.x
Subject(s) - reflux , chronic venous insufficiency , medicine , vein , great saphenous vein , duplex (building) , cardiology , pathophysiology , femoral vein , gastroenterology , duplex ultrasonography , surgery , vascular disease , disease , biology , genetics , dna
Aim: To compare the duplex‐derived parameters between patients with early, and those with advanced chronic venous insufficiency (CVI), and to determine the indicative parameters reflecting the progression of CVI. Methods: A total of 1132 limbs in 914 patients with of primary valvular incompetence were included. The clinical manifestations were categorized according to the CEAP (clinical, etiologic, anatomic, and pathophysiologic) classification, and the patients were divided into two groups: group I (C 1−3 E P ,A S,D,P ,P R ) and group (C 4−6 E P ,A S,D,P ,P R ). The distribution of venous insufficiency was determined, and the parameters assessed were the duration of reflux (s), the peak reflux velocity (cm/s), and the flow at peak reflux (ml/s). Results: There was no significant difference in overall superficial venous reflux between the groups. And the frequency of isolated deep and perforator incompetence did not differ between the groups. The duration of reflux did not improve the discrimination power between the groups. In contrast, the peak reflux velocity had significant discrimination power at the sapheno‐femoral junction (SFJ, p < 0.0001) and sapheno‐popliteal junction (SPJ, p = 0.0002), and in the greater saphenous vein (GSV, p < 0.0001), in the superficial femoral vein (SFV, p = 0.0041), and popliteal vein (POPV, p = 0.003). The peak reflux flow was significantly higher in group II at the SFJ ( p < 0.0001) and SPJ ( p = 0.0029), and in the GSV ( p < 0.0001), in the common femoral vein ( p = 0.006), in the SFV ( p = 0.0005), and POPV ( p = 0.0003). Conclusions: Superficial venous insufficiency may play a major role in the disease development of advanced CVI. The peak reflux velocity and peak reflux volume improve discrimination power between early‐stage and advanced CVI.