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029
Treatment of Fresh DDB Wounds with Allogenic Cultured Fibroblasts, Allogenic Cultured Dermal Substitute
Author(s) -
Kazutaka Soejima,
Takamitsu Nakano,
Hajime Matsumine,
Daiki Nakamori,
Motohiro Nozaki,
Kentaro Kubo,
Hiromichi Matsui,
Sizuko Kagawa,
Yoshimitsu Kuroyanagi
Publication year - 2004
Publication title -
wound repair and regeneration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.847
H-Index - 109
eISSN - 1524-475X
pISSN - 1067-1927
DOI - 10.1111/j.1067-1927.2004.abstractar.x
Subject(s) - hyaluronic acid , wound healing , medicine , fibroblast , andrology , chemistry , surgery , anatomy , in vitro , biochemistry
Aim: Multi‐center's clinical study for the application of the cultured dermal substitute (CDS) composed of hyaluronic acid and collagen spongy matrix with allogenic cultured fibroblasts 1 is in progress since 2001. In this study, effect of the CDS for the treatment of fresh DDB wounds was tested. Methods: Six cases of second‐degree burns, diagnosed as DDB by observation of blood stream of the dermal capillary using Compact Micro Vision System (Hi‐Scope ® , Hi Rox Co., Japan), were treated with the cultured allogenic fibroblasts, CDS. Results: The epithelialization of the wounds was obtained on 8.2 ± 2.6 (mean ± SD) days after the application. Conclusion: The results of our clinical experiences suggest that the allogenic cultured fibroblasts have beneficial effect on the wound healing of the DDB.