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The Doppler‐Derived Myocardial Performance Index Is Determined by Both Left Ventricular Systolic and Diastolic Function as Well as by Afterload and Left Ventricular Mass
Author(s) -
Lind Lars,
Andrén Bertil,
Ärnlöv Johan
Publication year - 2005
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.0742-2822.2005.03175.x
Subject(s) - afterload , preload , cardiology , medicine , ejection fraction , stroke volume , blood pressure , diastole , pulse pressure , population , hemodynamics , heart rate , heart failure , environmental health
Objectives: To investigate if the newly developed Doppler‐derived myocardial performance index (MPI, also denoted TEI‐index) is associated with variables reflecting both left ventricular (LV) systolic and diastolic function, as well as variables reflecting preload, afterload, and LV geometry. Material: An echocardiographic examination including Doppler was carried out in 446 men aged 70 in a population‐based survey (the ULSAM‐study, Uppsala Longitudinal Study of Adult Men). Results: In multiple regression analysis, MPI was independently associated with ejection fraction (P < 0.001), E/A ratio (P < 0.001), total peripheral resistance index (P < 0.001), stroke volume to pulse pressure ratio (P < 0.02), stroke index (P < 0.01), and LV mass (P < 0.04), but not with heart rate or blood pressure. Conclusion: The echocardiographically determined myocardial performance index is determined by both LV systolic and diastolic function as well as by afterload and left ventricular mass.