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HEPATITIS ASSOCIATED ANTIGEN (HAA) IN URINE FROM SERUM HAA POSITIVE RENAL TRANSPLANT RECIPIENTS
Author(s) -
Skinhøj Peter,
Steiness Ib
Publication year - 1973
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.0365-5563.1973.tb00004.x
Subject(s) - urine , urinary system , immunoelectrophoresis , medicine , kidney , antigen , hepatitis , immunology , pathology
Urine was examined for the presence of hepatitis associated antigen (HAA) by means of gel diffusion and immunoelectrophoresis in thirteen renal transplant recipients who were known serum carriers of HAA. Three 24‐hour urine collections were obtained from twelve of the patients and two from one. All unconcentrated urine specimens examined were HAA negative. After 500‐fold concentration HAA could be demonstrated in the urinary samples obtained from four of the patients. HAA urinary excretion was not related to any of the kidney or liver parameters studied. Antigenuria could not be explained by increased glomerular permeability suggesting that HAA may propagate in the renal parenchyma and/or in the urinary tract.