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New aspects in the biology of cutaneous B‐cell lymphomas
Author(s) -
Pimpinelli Nicola
Publication year - 2006
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.0303-6987.2006.00546.x
Subject(s) - pathology , lymphoma , cbcl , cell of origin , b cell , biology , medicine , immunology , cell , genetics , antibody , clinical psychology
Immunologic and molecular genetic studies greatly contributed to a better understanding and interpretation of the distinct clinico‐pathologic features of primary cutaneous B‐cell lymphomas (CBCL), which are the basis for the consensus WHO‐EORTC classification. There is increasingly accumulating evidence that these well defined clinico‐pathologic entities of CBCL have specific immunologic and molecular features, which further support their nosologic categorization as well as either interesting similarities with other extranodal B‐cell lymphomas or definite peculiarities as compared to nodal B‐cell lymphomas of similar histotype (specifically, follicle center lymphoma and diffuse large B‐cell lymphoma).