Pathobiology of CD30 +  cutaneous T‐cell lymphomas | Zendy

Kadin Marshall E. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Pathobiology of CD30 + cutaneous T‐cell lymphomas

Author(s) -

Kadin Marshall E.

Publication year - 2006

Publication title -

journal of cutaneous pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.597

H-Index - 75

eISSN - 1600-0560

pISSN - 0303-6987

DOI - 10.1111/j.0303-6987.2006.00507.x

Subject(s) - lymphomatoid papulosis , cd30 , anaplastic large cell lymphoma , lymphoma , cd43 , pathology , lymphoproliferative disorders , medicine , cancer research , cd20

CD30+ cutaneous lymphoproliferative disorders include lymphomatoid papulosis (LyP) and anaplastic large cell lymphoma (ALCL). LyP is associated with development of lymphoma in nearly 20% of patients. Herein is reviewed the clonal relationship of LyP to malignant lymphoma, the concept of a common stem cell for LyP and associated lymphomas, and the role of genetic instability in lymphomagenesis. The possible role of the CD30+ cell as a regulatory T‐cell is introduced and a model for progression of LyP to ALCL is illustrated.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research