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Classification of cutaneous T‐cell lymphoma: from Alibert to WHO‐EORTC
Author(s) -
Willemze Rein,
J. L. M. Meijer Chris
Publication year - 2006
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.0303-6987.2006.00494.x
Subject(s) - mycosis fungoides , lymphoma , medicine , pathology , dermatology , cutaneous lymphoma , dermatopathology , cutaneous t cell lymphoma
Cutaneous T‐cell lymphomas (CTCLs) represent a heterogeneous group of neoplasms originating from skin‐homing T cells that show considerable variation in clinical presentation, histological appearance, immuno‐ phenotype, and prognosis. This review provides a historic overview of the classification of CTCLs from the first description of a patient with mycosis fungoides in 1806 to the recently published WHO‐EORTC classification. Practical guidelines for the usage of the WHO‐EORTC classification and relevant features of new or newly defined entities such as subcutaneous panniculitis‐like T‐cell lymphoma, extranodal NK/T‐cell lymphoma, nasal type, primary cutaneous aggressive CD8‐positive cytotoxic T‐cell lymphoma, and cutaneous γ/δ T‐cell lymphoma are presented. The aim of this review is to contribute to a better communication between dermatologist and pathologist and in this way to a better diagnosis and classification of CTCLs.