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Localized cutaneous polyvinylpyrrolidone storage disease mimicking cheilitis granulomatosa
Author(s) -
Chi ChingChi,
Wang ShuHui,
Kuo Tsengtong
Publication year - 2006
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.0303-6987.2006.00476.x
Subject(s) - polyvinylpyrrolidone , reticular connective tissue , medicine , dermatology , pathology , chemistry , polymer chemistry
Polyvinylpyrrolidone (PVP), a polymer of the monomer N ‐vinylpyrrolidone with various molecular weights, was originally developed as a plasma expander. Currently, it is widely used in hair sprays, skin care products, fruit juices, and as a retarding agent in drugs such as procaine and hormones. PVP polymers with a molecular weight greater than 20,000 cannot be excreted by the kidneys and therefore are phagocytosed and permanently stored in the reticular endothelial system, leading to the so‐called PVP storage disease. We report a case of localized cutaneous PVP storage disease presenting with persistent upper lip swelling and mimicking cheilitis granulomatosa, which has never been reported before.