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Congenital Erosive and Vesicular Dermatitis with Reticulated Scarring
Author(s) -
Lian F.,
LI A.,
Maberry S.,
Cockerell C.
Publication year - 2005
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.0303-6987.2005.320ec.x
Subject(s) - medicine , scars , dermatology , eosinophilic , pathology , trunk , erythema , congenital disorder , scarring alopecia , surgery , scalp , biology , ecology
Congenital erosive and vesicular dermatitis healing with reticulated scarring is a rare entity presenting in the early childhood. It is manifest as crusted erosions and vesicles that heal relatively rapidly forming unique reticulated scars. Cohen first reported this entity in 1985 and since then, only ten patients have been reported. We herein report an additional case of this extremely unusual disorder. A 23 month‐old girl who was noted to have “rashes” and sores over her body at birth. Her twin sister was unaffected. She was born preterm at 35 weeks gestation but her developmental milestones have been within normal range. On exam she had depressed and somewhat macerated erosions and erythema primarily on her trunk, axillae, and ears. No vesicles or bullae were present. The skin biopsy showed neutrophilic and eosinophilic infiltrates with abundant crusting. Cultures were negative for infectious agents and direct immunofluorescent studies were also negative. Over the next two years she periodically developed erosions which healed quickly. However, the depressed reticulated scars have persisted and are more sensitive to sun exposure. This scarring disorder may be associated with mild ongoing blistering and must be distinguished from other congenital blistering disorders and immunobullous diseases. The pathophysiology remains unclear.