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Contact vitiligo following a strong patch test reaction to triglycidyl‐ p ‐aminophenol in an aircraft industry worker: case report and review of the literature
Author(s) -
Jappe U.,
Geier J.,
Hausen B. M.
Publication year - 2005
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.0105-1873.2005.00651.x
Subject(s) - epoxy , diglycidyl ether , patch test , vitiligo , dermatology , allergic contact dermatitis , contact dermatitis , contact allergy , medicine , patch testing , bisphenol a , surgery , allergy , chemistry , organic chemistry , immunology
Epoxy resin systems (ERSs) are a frequent cause of occupational allergic contact dermatitis. A 50‐year‐old patient developed eczematous skin lesions on the back of his hands, lower arms and eye lids, 2 months after he had started working in aircraft construction. Patch tests showed positive reactions at day 3 to nickel sulfate, epoxy resin based on diglycidyl ether of bisphenol F (DGEBF) and 1,4‐butanediol diglycidyl ether (1,4‐BDDGE). The chemical triglycidyl‐p‐aminophenol (TGPAP) applied at 1% and 0.1% induced the strongest (+++ positive) reaction. About 4 months after the patch test with TGPAP, the patient presented with 2 circular depigmented spots in the former TGPAP‐patch test areas. Dermatohistopathology confirmed the diagnosis of contact vitiligo.