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Irritant dermatitis following tape stripping
Author(s) -
Nybæk Hanne,
Knudsen DB,
Nielsen LF,
Karlsmark T,
Jemec GBE
Publication year - 2004
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.0105-1873.2004.0309af.x
Subject(s) - transepidermal water loss , erythema , stripping (fiber) , stoma (medicine) , adhesive , dermatology , irritation , medicine , chemistry , surgery , materials science , immunology , stratum corneum , composite material , pathology , organic chemistry , layer (electronics)
Repeated tape stripping of the skin associated with e.g. the use of stoma care products can cause irritant dermatitis. This experimental study in 12 healthy volunteers was designed to assess the effects of 3 chemically and physically different adhesives commonly used in stoma care products. Two different frequencies of stripping (daily vs twice weekly) were tested, and the various parameters of inflammation and barrier integrity were studied with established non‐invasive methods (Measurement of erythema, conductance, and Trans Epidermal Water Loss (TEWL)) on day 0, 4, 6, 10, 16, 22 and 28. All adhesives caused increases in all the studied parameters during the 28 day period compared to the corresponding non‐stripped values. Furthermore, daily stripping caused significantly greater inflammation and barrier disruption than stripping twice weekly. In conclusion, it was possible by measuring skin erythema, conductance and TEWL to detect different patterns of inflammatory changes and barrier disruption in areas treated with the 3 adhesives. As expected, more frequent stripping caused greater changes. These differences did however appear at different times during the study period, suggesting that the chemical and mechanical properties of the adhesives may affect the skin differently.