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Hydrolysed wheat protein: a new allergen in cosmetics and food
Author(s) -
Pecquet Catherine,
Bayrou O,
Vigan M,
Raison N,
Lauriere M
Publication year - 2004
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.0105-1873.2004.00309ev.x
Subject(s) - cosmetics , gluten , immunoglobulin e , wheat flour , food allergens , allergy , contact urticaria , allergen , food science , dermatology , chemistry , food allergy , medicine , immunology , contact dermatitis , antibody , organic chemistry
For the pas few years, mainly because of mad cow disease, hydrolysed wheat proteins (HWP) have been used in cosmetics and food as emulsifiers and stabilizers in replacement of bovine collagen. We report here contact urticaria to cosmetics induced by these HWP in 7 patients of which 6 had food allergy to modified gluten and the results of their immunological testing. These cases were regrouped through the french network REVIDAL‐GERDA. All 7 women developped contact urticaria immediatly after applying cosmetics (mainly facial cream), from different brands, containing HWP. Six of them had also anaphylactic reactions or urticaria after eating preserved foods or delicatessen which contained modified gluten. Neither had allergic reaction after eating broad or bread. Skin tests were positive with the cosmetics, HWP contained in them and, in case of food allergy, modified gluten. They were negative with natural wheat flour. Despite that, specific IgE to wheat flour were positive in 2 cases. Specific IgE to gluten were positive in 3 patients. Sera were also investigated for their specificity toward wheat proteins and various preparations of gluten. Individual variations of specificity were observed. All sera contained IgE reacting with both hydrolysed peptides and some native flour proteins. It appears that, from the medical history, allergy to cosmetics preceeded food allergy. In view of these elements, may be the use of HWP in cosmetics should be questionned.