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No suppression of nickel patch reactions by local betamethasone
Author(s) -
Lauerma Antti,
Molander Gerd,
Petman Leena,
Kannas Liisa
Publication year - 2004
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.0105-1873.2004.00309ee.x
Subject(s) - patch test , betamethasone , medicine , corticosteroid , patch testing , dermatology , contact dermatitis , skin patch , anesthesia , allergy , surgery , immunology
Background: Topical corticosteroids are usually banned on test areas prior to patch testing. The previous literature on the effect of topical corticosteroids is conflicting. Methods: Patients allergic to nickel sulphate were patch tested on 4 sites with nickel on Day 0. Intracutaneous betamethasone was injected to test sites on Day −1, Day 0 and Day 1. NaCl injection on Day −1 was control. The patch test reactions were evaluated clinically and with laser doppler. Observations: There were no differences in patch test reaction intensities on sites treated with intracutaneous betamethasone as compared to control. Conclusions: A single local dose of potent corticosteroid does not suppress allergic patch reactions to nickel. The current practice of avoiding topical corticosteroid use prior to patch testing should be re‐evaluated.