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Non‐pigmenting fixed drug eruption caused by allylisopropylacetylurea
Author(s) -
Numata Yukikazu,
Terui Tadashi,
Sasai Shu,
Sugawara Masayuki,
Kikuchi Katsuko,
Tagami Hachiro,
Aiba Setsuya
Publication year - 2003
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.0105-1873.2003.0212.x
Subject(s) - drug eruption , medicine , dermatology , trunk , patch testing , drug , surgery , contact dermatitis , allergy , pharmacology , immunology , ecology , biology
An unusual case of a non‐pigmenting fixed drug eruption caused by allylisopropylacetylurea is reported. Several hours after taking an analgesic (New Kaiteki A ® ), a 30‐year‐old Japanese woman, who had experienced similar eruptions several times after taking other analgesics, developed numerous variously sized, itchy, round‐to‐oval erythematous eruptions on the trunk and extremities. After she discontinued taking this drug, all such eruptions resolved within 2 weeks, without leaving postinflammatory pigmentation. Patch testing with New Kaiteki A ® itself and one of its active ingredients, allylisopropylacetylurea, on lesional skin, but not on uninvolved skin, showed positive erythematous reactions after 2 days.