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PROTEIN PHOSPHATASE INHIBITORY ACTIVITY IN EXTRACTS OF CULTURED BLUE‐GREEN ALGAE (CYANOPHYTA) 1
Author(s) -
Honkanen Richard E.,
Caplan Faith R.,
Baker Kathleen K.,
Baldwin Cynthia L.,
Bobzin Steven C.,
Bolis Christine M.,
Cabrera Gabriela M.,
Johnson Louis A.,
Jung Jee H.,
Larsen Linda K.,
Levine Ira A.,
Moore Richard E.,
Nelson Carrie S.,
Patterson Gregory M. L.,
Tschappat Kathryn D.,
Tuang Grace D.,
Boynton Alton L.,
Arment Anthony R.,
An Jisi,
Carmichael Wayne W.,
Rodland Karin D.,
Magun Bruce E.,
Lewin Ralph A.
Publication year - 1995
Publication title -
journal of phycology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.85
H-Index - 127
eISSN - 1529-8817
pISSN - 0022-3646
DOI - 10.1111/j.0022-3646.1995.00478.x
Subject(s) - biology , cyanobacteria , serine , algae , threonine , phosphatase , inhibitory postsynaptic potential , biochemistry , blue green algae , enzyme , green algae , botany , bacteria , genetics , neuroscience
A large‐scale screening program was initiated to evaluate laboratory‐cultured blue‐green algae (cyanobacteria) as a source of novel compounds with inhibitory activity against certain serine/threonine protein phosphatases. Over 1600 extracts, representing 816 cyanophyte strains with broad habitat and taxonomic diversity, were screened. Inhibitors were identified in extracts produced from all orders tested except Chamaesiphonales, and the family Stigonemataceae was found to contain proportionally more inhibitors as compared to the total screen .