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ANTINEOPLASTIC ACTIVITY OF CULTURED BLUE‐GREEN ALGAE (CYANOPHYTA) 1
Author(s) -
Patterson Gregory M. L.,
Baldwin Cynthia L.,
Bolis Christine M.,
Caplan Faith R.,
Karuso Helen,
Larsen Linda K.,
Levine Ira A.,
Moore Richard E.,
Nelson Carrie S.,
Tschappat Kathryn D.,
Tuang Grace D.,
Furusawa Eiichi,
Furusawa Shinobu,
Norton Ted R.,
Raybourne Richard B.
Publication year - 1991
Publication title -
journal of phycology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.85
H-Index - 127
eISSN - 1529-8817
pISSN - 0022-3646
DOI - 10.1111/j.0022-3646.1991.00530.x
Subject(s) - biology , cyanobacteria , blue green algae , algae , botany , green algae , bacteria , genetics
A large‐scale screening program was initiated to evaluate laboratory‐cultured blue‐green algae (cyanobacteria) as a source of novel antineoplastic agents. Approximately 1000 cyanophyte strains from diverse habitats were cultured to provide extracts for testing. The screening program identified the families Scytonemataceae and Stigonemataceae as prolific producers of novel cytotoxic compounds. Rates of rediscovery of known compounds were relatively low.