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Ictal Smile Lateralizes to the Right Hemisphere in Childhood Epilepsy
Author(s) -
Fogarasi András,
Janszky József,
Siegler Zsuzsanna,
Tuxhorn Ingrid
Publication year - 2005
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.0013-9580.2005.47704.x
Subject(s) - epilepsy , cortical dysplasia , ictal , lateralization of brain function , cortex (anatomy) , psychology , audiology , laterality , medicine , electroencephalography , neuroscience
Summary: Purpose: To analyze the localizing and lateralizing value of ictal smile (IS) in childhood epilepsy. Methods: Incidence of IS in 309 videotaped seizures of 114 consecutive patients younger than 12 years with refractory frontal, temporal, or posterior cortex epilepsy were assessed. Results: Among patients with right‐sided epileptogenic zone, 12 (21%) of 57 had IS, whereas in patients with left‐sided epilepsy, IS occurred only in one patient (1.8%; p < 0.01, χ 2 test). The incidence of IS was 11%, 3%, and 26% in the frontal, temporal, and posterior cortex subgroups, respectively. Logistic regression revealed that the localization of the epileptogenic region in the posterior cortex (p < 0.01), focal cortical dysplasia etiology (p = 0.012), and right‐sided lateralization (p = 0.025) were independently associated with the presence of IS. Conclusions: Childhood IS lateralizes to the right hemisphere and localizes more frequently in the posterior cortex epilepsy.