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Functional MRI and Wada Determination of Language Lateralization: A Case of Crossed Dominance
Author(s) -
Ries Michele L.,
Boop Frederick A.,
Griebel May L.,
Zou Ping,
Phillips Nicholas S.,
Johnson Sterling C.,
Williams Jane P.,
Helton Kathleen J.,
Ogg Robert J.
Publication year - 2004
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.0013-9580.2004.04403.x
Subject(s) - wada test , lateralization of brain function , psychology , magnetic resonance imaging , functional magnetic resonance imaging , neurosurgery , dominance (genetics) , neuroscience , epilepsy , epilepsy surgery , audiology , medicine , radiology , psychiatry , biochemistry , chemistry , gene
Summary: The Wada test has historically been the conventional procedure for determining language lateralization before neurosurgery. However, functional magnetic resonance imaging (fMRI) offers a less invasive alternative to the Wada procedure. Research indicates that the two techniques used together may provide comparable, and sometimes complementary, information that results in improved prediction of postsurgical language ability. We present a case in which use of fMRI in conjunction with Wada testing provided complementary information about language lateralization before neurosurgical resection of a mesial temporal subependymoma for seizure control in a patient with schizencephaly.