Open AccessValues of β‐human chorionic gonadotropin as a risk factor for tubal obstruction after tubal pregnancy
Author(s) -
Elito Julio,
Han Kyung Koo,
Camano Luiz
Publication year - 2005
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/j.0001-6349.2005.00836.x
Subject(s) - medicine , gynecology , hysterosalpingography , pregnancy , human chorionic gonadotropin , fallopian tube , obstetrics , gonadotropin , odds ratio , ectopic pregnancy , infertility , hormone , genetics , biology
Aim. The hysterosalpingography (HSG) was evaluated after the clinical treatment of tubal pregnancy and the possible risk of tubal obstruction through the following parameters: β‐human chorionic gonadotropin (β‐hCG) levels, size of the adnexal mass, aspects of the image at ultrasound, and color Doppler. Methods. Eighty patients were submitted to HSG after tubal pregnancy treatment from April 1994 to February 2002. Fifty received expectant management and 30 were treated with single‐dose methotrexate (MTX) (50 mg/m 2 intramuscularly). Results. The patency of the ipsilateral tube was 84% and 78% after the MTX and expectant treatments, respectively ( P > 0.05). After the logistic regression was performed, it was observed that levels of β‐hCG >5000 mUI/ml were directly related to the tubal obstruction risk, odds ratio = 11.79 (95% CI = 2.27–61.32). Other variables were not directly related to the tubal obstruction risk. Conclusions. In this study, the probability of ipsilateral tubal obstruction depends on the β‐hCG levels. The increase in β‐hCG levels is followed by an enhancement in tubal obstruction risk. Therefore, the β‐hCG may be effective for the prognostic of the reproductive future of these patients.