Open AccessThe effect of magnesium sulfate treatment on serum cardiac troponin I levels in preeclamptic women
Author(s) -
Atalay Cemal,
Erden Gönül,
Turhan Turan,
Yildiran Gülbin,
SaraÇoglu Ö. Ferit,
Koca Yüksel
Publication year - 2005
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/j.0001-6349.2005.00667.x
Subject(s) - medicine , preeclampsia , troponin i , troponin , gestational age , gestation , obstetrics , pregnancy , gastroenterology , cardiology , myocardial infarction , genetics , biology
Aim. To investigate serum cardiac troponin I levels before and after magnesium sulfate treatment in preeclamptic pregnant women. Materials and methods. Fifty‐five pregnant women were included in the prospectively planned study. Study group patients ( n = 25) were pregnant women hospitalized with a preeclampsia diagnosis while the control group ( n = 30) were pregnant women with no medical or obstetric problem who had been attending the antenatal clinic. Serum cardiac troponin I levels were compared in the normal pregnant women and in preeclamptic pregnant women. These levels were also compared in the preeclamptic women before and after magnesium sulfate treatment. Mann–Whitney U ‐test was used for statistical analysis. Results. Groups were similar with respect to age, gravity, parity, and gestational age. The median serum cardiac troponin I levels in preeclamptic patients was 0.20 ng/ml (0.02–4.53) before treatment and 0.09 ng/ml (0.02–3.91) after treatment, while it was 0.02 ng/ml (0.0–0.05) in the control group. The serum cardiac troponin I level in the preeclamptic group was significantly high ( P < 0.01), and pretreatment values in this group were significantly higher compared with post‐treatment values ( P < 0.01) Conclusion. Cardiac troponin I is a sensitive parameter for indicating minor myocardial damage which may occur in preeclampsia and for evaluating the efficiency of magnesium sulfate treatment.