Open AccessPeriod of gestational diabetes mellitus diagnosis and maternal and fetal morbidity
Author(s) -
Barahona María José,
Sucunza Nuria,
GarcíaPatterson Apolonia,
Hernández Marta,
Adelantado Juan M.,
Ginovart Gemma,
De Leiva Alberto,
Corcoy Rosa
Publication year - 2005
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/j.0001-6349.2005.00634.x
Subject(s) - medicine , gestational diabetes , obstetrics , pregnancy , apgar score , logistic regression , retrospective cohort study , fetus , confounding , diabetes mellitus , offspring , gestational age , gestation , endocrinology , genetics , biology
Background. The aim of the study was to analyze the association between the period of diagnosis of gestational diabetes mellitus (GDM) and maternal and neonatal outcome. Methods. In this retrospective study, 1708 offspring (1571 singleton, 119 twins, and 18 triplets) born to women with GDM who attended the Diabetic and Pregnancy Clinic were included. Pregnancies were divided into three groups according to the gestational age at GDM diagnosis. The association of the period of diagnosis with maternal and fetal outcome was assessed adjusting for potentially confounding variables (logistic regression analysis). Results. The period of diagnosis was a predictor in two out of three maternal outcomes (pregnancy‐induced hypertension and insulin treatment) and in four out of 12 fetal outcomes (preterm birth, 5‐min Apgar <7, perinatal mortality, and hyperbilirubinemia). Whereas pregnancy‐induced hypertension was higher in women diagnosed with GDM in the second period, the other outcomes displayed higher occurrences with earlier diagnosis. Conclusions. Diagnosis of GDM earlier in pregnancy is a predictor of adverse maternal and neonatal outcome.