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Is the ARX index a more sensitive indicator of anesthetic depth than the bispectral index during sevoflurane/nitrous oxide anesthesia?
Author(s) -
Nishiyama T.,
Matsukawa T.,
Hanaoka K.
Publication year - 2004
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.0001-5172.2004.00468.x
Subject(s) - bispectral index , sevoflurane , anesthesia , medicine , nitrous oxide , anesthetic , propofol , laryngeal mask airway , airway
Background: During general anesthesia, hypnotic components have been monitored with electroencephalogram. The bispectral index is derived from a cortical electroencephalogram, but the A‐line ARX index is the electroencephalographic response to auditory stimuli. The purpose of this study was to compare the changes of the A‐line ARX index and the bispectral index during sevoflurane – nitrous oxide anesthesia. Methods: One hundred females aged 30–60 years, and scheduled for partial mastectomy, were divided into two groups. Anesthesia was induced with sevoflurane 5% and nitrous oxide in oxygen for 3 min. A laryngeal mask airway was inserted, and anesthesia was maintained with sevoflurane 1–2% and nitrous oxide in oxygen. During surgery, the sevoflurane end‐tidal concentration was kept at 0.5%, 1%, or 2% for 5 min before each measurement. Blood pressure, heart rate, and the A‐line ARX index (n = 50), and the bispectral index (n = 50) were measured. Results: Blood pressure and heart rate increased following laryngeal mask airway insertion and blood pressure decreased at 2% sevoflurane in both groups similarly. The A‐line ARX index, but not the bispectral index, increased significantly by laryngeal mask airway insertion and skin incision. The A‐line ARX index decreased at 2% sevoflurane compared with 0.5%, while the bispectral index remained unchanged. Conclusion: During sevoflurane‐nitrous oxide anesthesia, the A‐line ARX index might be a more sensitive indicator of anesthetic depth than the bispectral index.