Open AccessGroin wound infection after vascular exposure ( GIVE ) multicentre cohort study
Author(s) -
Brenig Llwyd Gwilym,
Athanasios Saratzis,
Ruth Benson,
Rachael Forsythe,
George Dovell,
Nikesh Dattani,
Tristan Lane,
Joseph Shalhoub,
David C. Bosanquet,
Brenig Llwyd Gwilym,
Louise Hitchman,
Nikesh Dattani,
Sarah Onida,
George Dovell,
Rachael Forsythe,
David C. Bosanquet,
Brenig Llwyd Gwilym,
Athanasios Saratzis,
Graeme K. Ambler,
David C. Bosanquet,
Ruth Benson,
Sandip Nandhra,
Joseph Shalhoub,
Athanasios Saratzis,
Sarah Onida,
Rachael Forsythe,
Nikesh Dattani,
Graeme K. Ambler,
David C. Bosanquet,
Philip W. Stather,
Aminder Singh,
Enrico Mancuso,
Mohedin Arifi,
Mohamed Altabal,
Ahmed Elhadi,
Abdulmunem Althini,
Hazem Ahmed,
Huw Ob Davies,
Madhu Rangaraju,
Maciej Juszczak,
Jonathan Nicholls,
Nicholas Platt,
J Olivier,
Emily Kirkham,
David J. Cooper,
Iain Roy,
Gareth Harrison,
James Ackah,
Devender Mittapalli,
Ian Barry,
Toby Richards,
Ahmed Elbasty,
Hayley Moore,
Adnan Bajwa,
Andrew Duncan,
Andrew Batchelder,
Tryfon Vanias,
Matthew Brown,
Athanasios Saratzis,
Trixie Yap,
Lucy Green,
George E. Smith,
Katherine Hurst,
Daniel Urriza Rodriguez,
Ella Schofield,
Hannah Danbury,
Tom Wallace,
J. S. Forsyth,
Amy Stimpson,
Luke Hopkins,
Kamran Mohiuddin,
Sandip Nandhra,
Ghazaleh MohammadiZaniani,
Konstantinos Tigkiropoulos,
Ahmed Shalan,
Khalid Bashar,
R.C. Sam,
Craig Forrest,
Samuel Debono,
Keith Hussey,
Rachel Falconer,
Salil Korambayil,
Ciaran Brennan,
Thomas J. Wilson,
Aled Jones,
T Amy Hardy,
Hannah Burton,
Andrew J. Cowan,
Ummul Contractor,
Elaine Townsend,
Olivia Grant,
Michelle Cronin,
Michael Rocker,
Danielle Lowry,
Annie Clothier,
Dafydd Locker,
Rachael Forsythe,
Olivia McBride,
Calvin Eng,
Russell W. Jamieson,
Nishath Altaf,
Fernando Picazo,
Kishore Sieunarine,
Ruth Benson,
Alexander Crichton,
Nikesh Dattani,
Tasleem Akhtar,
Helen Suttenwood,
Francesca Guest,
Bethany Wardle,
George Dovell,
Natasha Chinai,
Graeme K. Ambler,
David C. Bosanquet,
Robert J. Hinchliffe,
Timothy Beckitt,
Arsalan Wafi,
Ankur Thapar,
Paul Moxey,
Tristan Lane,
Ryan Preece,
Kalnisha Naidoo,
Benjamin O. Patterson,
Claire Perrott,
Joseph Shalhoub,
Thomas Aherne,
Ahmed Hassanin,
Emily Boyle,
Bridget Egan,
Sean Tierney,
Shaneel Patel,
Panagiota Birmpili,
Sandhir Kandola,
Simon Neequaye,
Muhammed Elhadi,
Ahmed Msherghi,
Ala Khaled,
Lewis Meecham,
Owain Fisher,
Ansar Mahmood,
David Milgrom,
Kerry Burke,
Faris Saleh,
Tariq AlSamarneh
Publication year - 2021
Publication title -
international wound journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.867
H-Index - 63
eISSN - 1742-481X
pISSN - 1742-4801
DOI - 10.1111/iwj.13508
Subject(s) - medicine , groin , surgery , prospective cohort study , incidence (geometry) , cohort study , cohort , mortality rate , physics , optics
Surgical site infections (SSIs) of groin wounds are a common and potentially preventable cause of morbidity, mortality, and healthcare costs in vascular surgery. Our aim was to define the contemporaneous rate of groin SSIs, determine clinical sequelae, and identify risk factors for SSI. An international multicentre prospective observational cohort study of consecutive patients undergoing groin incision for femoral vessel access in vascular surgery was undertaken over 3 months, follow‐up was 90 days. The primary outcome was the incidence of groin wound SSI. 1337 groin incisions (1039 patients) from 37 centres were included. 115 groin incisions (8.6%) developed SSI, of which 62 (4.6%) were superficial. Patients who developed an SSI had a significantly longer length of hospital stay (6 versus 5 days, P = .005), a significantly higher rate of post‐operative acute kidney injury (19.6% versus 11.7%, P = .018), with no significant difference in 90‐day mortality. Female sex, Body mass index≥30 kg/m 2 , ischaemic heart disease, aqueous betadine skin preparation, bypass/patch use (vein, xenograft, or prosthetic), and increased operative time were independent predictors of SSI. Groin infections, which are clinically apparent to the treating vascular unit, are frequent and their development carries significant clinical sequelae. Risk factors include modifiable and non‐modifiable variables.