Open AccessPain reduction of topical sevoflurane vs intravenous opioids in pressure ulcers
Author(s) -
FernándezGinés F. Dámaso,
CortiñasSáenz Manuel,
AgudoPonce Desirée,
NavajasGómez de Aranda Ana,
MoralesMolina José A.,
FernándezSánchez Carmen,
SierraGarcía Francisco,
MateoCarrasco Héctor
Publication year - 2020
Publication title -
international wound journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.867
H-Index - 63
eISSN - 1742-481X
pISSN - 1742-4801
DOI - 10.1111/iwj.13235
Subject(s) - medicine , sevoflurane , anesthesia , refractory (planetary science) , adverse effect , analgesic , surgery , physics , astrobiology
Recently, it has been reported that topical irrigations of liquid sevoflurane on the bed of painful wounds produce a rapid, intense, and lasting analgesic effect. In this paper, A cohort of 112 patients with painful pressure ulcers who were refractory to opioids (or who exhibited undesirable adverse events to them) was treated with topical sevoflurane as per local institutional policy. These patients were recruited from an intensive care unit for a period of 3 years. The main aim was to determine the effectiveness of topical sevoflurane in reducing the pain of PUs and reducing the ulcer area. Study findings are reported and discussed herein and suggest that sevoflurane is a viable and promising treatment option for PUs.