Open AccessVegetating erosive cutaneous lesions and pyogenic granuloma in the course of mucous membrane pemphigoid: a case report and review of literature
Author(s) -
Jakubowska Beata,
Kowalewski Cezary,
Ishii Norito,
Hashimoto Takashi,
Wozniak Katarzyna
Publication year - 2018
Publication title -
international wound journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.867
H-Index - 63
eISSN - 1742-481X
pISSN - 1742-4801
DOI - 10.1111/iwj.12943
Subject(s) - medicine , conjunctiva , pyogenic granuloma , pathology , mucous membrane , intertriginous , pemphigoid , dermatology , autoantibody , conjunctival diseases , bullous pemphigoid , immunology , lesion , antibody , disease
Mucous membrane pemphigoid (MMP) is a group of chronic autoimmune sub‐epithelial blistering disorders, which mostly affect the oral mucosa and the conjunctiva. MMP is very diverse in terms of both the clinical and immunological features (IgG and IgA autoantibodies may react with different antigens). MMP can be induced by infections and medication, including ophthalmologic medication, which may lead to the development of eye lesions. In contrast, a vegetating variant of MMP is extremely rare. Here, we report an MMP case that demonstrated unusual clinical features, that is, pyogenic granulomas on the conjunctivae and extensive vegetating erosions on the skin of intertriginous regions. All these lesions were considered to be induced by unconventional medication containing arsenic.