Open AccessLength of surgery and pressure ulcers risk in cardiovascular surgical patients: a dose–response meta‐analysis
Author(s) -
Chen HongLin,
Shen WangQin,
Liu Peng,
Liu Kun
Publication year - 2017
Publication title -
international wound journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.867
H-Index - 63
eISSN - 1742-481X
pISSN - 1742-4801
DOI - 10.1111/iwj.12722
Subject(s) - medicine , meta analysis , funnel plot , surgery , significant difference , relative risk , confidence interval , publication bias
The aim of this study was to assess the relationship between length of surgery ( LOS ) and pressure ulcer ( PU ) risk in cardiovascular surgery patients. PubMed and Web of Science were systematically searched. We compared LOS difference between PU (+) group and PU (‐) group. We also examined the dose–response effect of this relationship. The mean LOS in the PU (+) groups ranged from 252·5 to 335·7 minutes, compared with 233·0 to 298·3 minutes in PU (−) groups. The LOS was higher in PU (+) groups compared with PU (−) groups [weighted mean difference ( WMD ) = 36·081 minutes; 95% CI : 21·640–50·522 minutes; Z = 4·90, P = 0·000]. The funnel plot showed no publication bias. A significant dose–response association was also found between the LOS and the risk of surgery‐related pressure ulcers ( SRPU , model χ 2 = 9·29, P = 0·000). In the linear model, the PU OR was 1·296 (95% CI 1·097–1·531) for a 60‐minute increase in the LOS intervals and 13·344 (95% CI 2·521–70·636) for a 600‐minute increase. In a spline model, the OR of PU increased almost linearly along with the LOS . Our meta‐analysis indicated that LOS was an important risk factor for pressure ulcers in cardiovascular surgical patients.