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Hemopoietic tissue volume is a heritable trait in the schistosome‐transmitting snail Biomphalaria glabrata
Author(s) -
Sullivan John T.,
Beltran Roxxana V.,
Cruz Brandon C.,
Manuel Rhea A.,
White John K.
Publication year - 2016
Publication title -
invertebrate biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.486
H-Index - 42
eISSN - 1744-7410
pISSN - 1077-8306
DOI - 10.1111/ivb.12121
Subject(s) - biomphalaria glabrata , biology , snail , juvenile , hemolymph , anatomy , zoology , mitotic index , mitosis , ecology , andrology , schistosoma mansoni , genetics , schistosomiasis , helminths , medicine
The anterior pericardial wall or amebocyte‐producing organ ( APO ) is a site of hemocyte formation in the schistosome‐transmitting snail Biomphalaria glabrata . Histological sections of the APO s of adult schistosome‐resistant Salvador strain snails, and two schistosome‐susceptible M‐line strains, BRI ‐M and USF ‐M, showed qualitatively differing amounts of hemopoietic tissue ( HT ), with Salvador> BRI ‐M> USF ‐M. Adult Salvador snails also had a significantly higher concentration of hemocytes in the hemolymph than the two M‐Line strains. In juvenile snails of the same three strains, measurements of total APO HT volume confirmed the qualitative differences seen in adults, and differences between the three strains were statistically significant. Crosses between Salvador (large HT volume) and USF ‐M (small HT volume) show that a large HT volume is dominant in juvenile F 1 s. Analysis of the distribution of HT volume among F 2 s shows it to be a quantitative trait. Although USF ‐M juvenile F 0 s had a significantly lower APO HT volume than that of BRI ‐M F 0 s, they had a significantly higher mitotic index, possibly as a compensatory mechanism. Salvador APO allografts maintained HT volume and mitotic activity equally well in USF ‐M and Salvador recipients after 2 weeks, suggesting that the low HT volume in USF ‐M snails may result from a developmental defect rather than a lack of HT ‐supportive plasma factors.