Open AccessPopulation‐based assessment of risks for severe COVID‐19 disease outcomes
Author(s) -
Zerbo Ousseny,
Lewis Ned,
Fireman Bruce,
Goddard Kristin,
Skarbinski Jacek,
Sejvar James J.,
AzzizBaumgartner Eduardo,
Klein Nicola P.
Publication year - 2022
Publication title -
influenza and other respiratory viruses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.743
H-Index - 57
eISSN - 1750-2659
pISSN - 1750-2640
DOI - 10.1111/irv.12901
Subject(s) - medicine , covid-19 , disease , population , comorbidity , pandemic , cause of death , demography , pediatrics , emergency medicine , infectious disease (medical specialty) , environmental health , sociology
Among approximately 4.6 million members of Kaiser Permanente Northern California, we examined associations of severe COVID‐19 with demographic factors and comorbidities. As of July 23, 2021, 16 182 had been hospitalized, 2416 admitted to an ICU, and 1525 died due to COVID‐19. Age was strongly associated with hospitalization, ICU admission, and death. Black persons and Hispanic ethnicity had higher risk of death compared with Whites. Among the comorbidities examined, Alzheimer's disease was associated with the highest risk for hospitalization (aHR 3.19, CI: 2.88–3.52) and death (aHR 4.04, CI: 3.32–4.91). Parkinson's disease had the second highest risk of death (aHR = 2.07, CI: 1.50–2.87).