Open AccessGenetic diversity of respiratory enteroviruses and rhinoviruses in febrile adults, Singapore, 2007‐2013
Author(s) -
Linster Martin,
Donato Celeste,
Mah Marcus G.,
Grau Miguel L.,
Low Jenny G.,
Ooi Eng Eong,
Su Yvonne C.F.,
Smith Gavin J.D.,
Vijaykrishna Dhanasekaran
Publication year - 2020
Publication title -
influenza and other respiratory viruses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.743
H-Index - 57
eISSN - 1750-2659
pISSN - 1750-2640
DOI - 10.1111/irv.12662
Subject(s) - rhinovirus , phylogenetic tree , serotype , genetic diversity , enterovirus , virology , biology , population , medicine , genetics , virus , gene , environmental health
To understand the genetic diversity and patterns of circulation of rhinoviruses (RV) and enteroviruses (EV) in Singapore, we retrospectively screened 2950 nasal swab samples collected from adults presenting to primary care services with signs of febrile illness in Singapore during 2007‐2013 using sequencing and phylogenetic methods. Through sequencing and phylogenetic analysis, our results show the year‐round circulation of the three rhinovirus species, A, B, and C. A diverse set of RV/EV serotypes were detected in Singapore with a predominance of RV‐A in all years, whereas serotypes EV‐C A21 and EV‐D68 were only sporadically detected. This study highlights the previously unrecognized diversity and burden in the adult population in Singapore.