Open AccessAn avian influenza virus A(H7N9) reassortant that recently emerged in the United States with low pathogenic phenotype does not efficiently infect swine
Author(s) -
Powell Joshua D.,
Abente Eugenio J.,
Torchetti Mia K.,
Killian Mary L.,
Vincent Amy L.
Publication year - 2019
Publication title -
influenza and other respiratory viruses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.743
H-Index - 57
eISSN - 1750-2659
pISSN - 1750-2640
DOI - 10.1111/irv.12631
Subject(s) - virology , influenza a virus subtype h5n1 , virus , biology , highly pathogenic , outbreak , transmission (telecommunications) , avian influenza virus , influenza a virus , viral shedding , phenotype , gene , genetics , electrical engineering , engineering
In 2017, outbreaks of low and highly pathogenic avian H7N9 viruses were reported in four States in the United States. In total, over 270 000 birds died or were culled, causing significant economic loss. The potential for avian‐to‐swine transmission of the U.S. avian H7N9 was unknown. In an experimental challenge in swine using a representative low pathogenic H7N9 (A/chicken/Tennessee/17‐007431‐3/2017; LPAI TN /17) isolated from these events, no infectious virus in the upper and minimal virus in the lower respiratory tract was detected, nor was lung pathology or evidence of transmission in pigs observed, indicating that the virus cannot efficiently infect swine.