Open AccessComparison of the three waves of avian influenza A(H7N9) virus circulation since live poultry markets were permanently closed in the main urban areas in Zhejiang Province, July 2014‐June 2017
Author(s) -
Cheng Wei,
Wang Xiaoxiao,
Shen Ye,
Yu Zhao,
Liu Shelan,
Cai Jian,
Chen Enfu
Publication year - 2018
Publication title -
influenza and other respiratory viruses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.743
H-Index - 57
eISSN - 1750-2659
pISSN - 1750-2640
DOI - 10.1111/irv.12532
Subject(s) - epidemiology , influenza a virus subtype h5n1 , veterinary medicine , rural area , medicine , virus , demography , geography , environmental health , virology , pathology , sociology
Background The sudden increase in the number of human cases infected with avian influenza A(H7N9) virus after September 2016 raised global concern. Objectives To assess the changes in epidemiological characteristics of H7N9 cases since the massive closure of live poultry markets ( LPM s) in the main urban areas in Zhejiang province. Methods We used descriptive statistics to compare epidemiological characteristics of the three distinct waves of H7N9 cases in Zhejiang province. The rural or urban cases were defined according to the location where the patients had exposure within 2 weeks before illness onset. Results Between July 2014 and June 2017, 166 H7N9 cases were reported in Zhejiang province, with 45, 34, and 87 cases reported in the third, fourth, and fifth wave, respectively. Across the three waves, most reported cases were from rural areas. A similar percentage of cases in all three waves reported exposure to LPM s, raising poultry at home or around the house, as well as occupational exposure. Compared to the third (80.00%) and fourth wave (70.59%), a significantly larger proportion of cases from the non‐ LPM s closure areas were observed in the fifth wave (89.66%) ( P = .034). Conclusion Epidemiological characteristics of human cases infected with avian influenza A(H7N9) virus had generally remained unchanged since the massive closure of LPM s in the main urban area of Zhejiang province. The sudden increase in the number of H7N9 cases in the fifth wave was mainly attributed to the excessive cases reported from areas where LPM s were not permanently closed.