Estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in South Africa, 2015 | Zendy

McAnerney Johanna M. | Zendy; Walaza Sibongile | Zendy; Tempia Stefano | Zendy; Blumberg Lucille | Zendy; Treurnicht Florette K. | Zendy; Madhi Shabir A. | Zendy; ValleyOmar Ziyaad | Zendy; Cohen Cheryl | Zendy

Open Access

Estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in South Africa, 2015

Author(s) -

McAnerney Johanna M.,

Walaza Sibongile,

Tempia Stefano,

Blumberg Lucille,

Treurnicht Florette K.,

Madhi Shabir A.,

ValleyOmar Ziyaad,

Cohen Cheryl

Publication year - 2017

Publication title -

influenza and other respiratory viruses

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.743

H-Index - 57

eISSN - 1750-2659

pISSN - 1750-2640

DOI - 10.1111/irv.12436

Subject(s) - influenza vaccine , seasonal influenza , medicine , virology , influenza a virus , influenza season , flu season , virus , outpatient clinic , live attenuated influenza vaccine , vaccine efficacy , vaccination , covid-19 , infectious disease (medical specialty) , disease

Trivalent seasonal influenza vaccine effectiveness during the 2015 season in South Africa was assessed using a test‐negative case control study design. Influenza A(H1N1)pdm09 was the dominant circulating strain. Overall influenza vaccine coverage was 3.2% (29/899). The vaccine effectiveness estimate, against any influenza virus infection, adjusted for age, underlying conditions and timing within season was 46.2% (95% CI: −23.5 to 76.5), and 53.6% (95% CI: −62.6 to 80.3) against influenza A(H1N1)pdm09.

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